Assistant Professor
B.S. Chemistry 1991, University of Illinois at Urbana-Champaign
Ph.D. Organic Chemistry 1997, University of Wisconsin-Madison
Postoctoral Research 1997-1999 The Pennsylvania State University
Visiting Assistant Professor 1999-2000, Centenary College of Louisiana
Assistant Professor of Chemistry 2000-present, Wittenberg University
 

Contact Information:

Dr. Peter E. Hanson
Assistant Professor of Chemistry
Wittenberg University
P.O. Box 720
Springfield, OH 45501
(937) 327-6455
phanson@wittenberg.edu

Courses

                                Chemistry 121, Models of Chemical Systems (link)
                                Chemistry 162, Fundamentals of Chemical Systems (link)
                                Chemistry 201, Organic Chemistry I (link)
                                Chemistry 282, Qualitative Organic Analysis Laboratory (link)
                                Chemistry 302, Organic Chemistry II (link)
                                Chemistry 303, Advanced Organic Chemistry (link)
 

Research Interests

Role of pheromones in acarines, Preparation of protective groups for organic synthesis
 

Current Research

    Pheromone Biosynthesis

    This research, conducted in collaboration with Dr. Jay Yoder of the Biology department, seeks to determine the molecular origin of 2,6-dichlorophenol (2,6-DCP), the only known sex pheromone of the American dog tick, Dermacentor variabilis (Say).  Our approach to this investigation involves the use of instrumentation and techniques commonly utilized in modern chemical research laboratories, including GC-MS, NMR and the preparation of non radioisotope containing compounds.  The project also involves quantification of the ability of 2,6-DCP mimics to elicit biological behavior.  Once the production pathway of 2,6-DCP is determined, alterations of the biosynthesis of these chemical cues (i.e.- sex pheromones) that modulate mate attraction could serve as an effective mechanism for control of the species.  This research is supported by a grant from the Merck/AAAS Undergraduate Science Research Program. (Meck/AAAS USRP homepage)

    Protective Groups in Organic Synthesis

    The ability of an organic chemist to efficiently carry out a series of synthetic steps, beginning with a single compound, depends in part on the avoidance of undesirable side reactions.  While many organic reactions take place with greater than 80% yield of desired product under controlled conditions, a series of 5 steps of  this efficiency will result in an overall yield of  33%, or a loss of 67% of the initial material.  To avoid this "loss of yield," it is often prudent to protect portions of the molecule from undesired transformation.  In this research, methods to protect carbon-carbon double bonds are being investigated.

Contributions

    Peer-Reviewed Publications (* denotes student authors)

"Asymmetric Oxidation of Sulfides with H₂O₂ Catalyzed by (salen)Mn(III) Complexes", Palucki, M.; Hanson, P.E.; Jacobsen, E.N.Tetrahedron Lett. 1992, 33, 7111.

"Z-(O-benzoyl)-2-aci-nitro-2-phenylacetonitrile" Powell, D.R.; Hanson, P.E.;Gellman, S.H. Acta Cryst . C 1996, c52, 2945.

"Mechanistic Comparison of Artificial Chaperone-assisted and Unassisted Refolding of Carbonic Anhydrase B" Hanson, P.E.; Gellman, S.H. Folding & Design 1998, 3, 457.

"Artificial Chaperone-Assisted Refolding of Citrate Synthase", Daugherty, D.L., Rozema, D.B., Hanson, P.E., Gellman, S.H.  J. Biol. Chem. 1998, 273, 33961.

“Biological Activity of Chlorinated Phenols in the American Dog Tick, Dermacentor variabilis (Acari: Ixodidae)” Hanson, P.E., Yoder, J.A.; Pizzuli, J.L.*, and Johnson, A.E.*. International Journal of Acarology 2002, 28(1), 55.

“On the Role of 2,6-Dichlorophenol as a Tick Sex Pheromone (Acari: Ixodidae)” Yoder, J.A., Hanson, P.E., Sanders, C. I.* and Burke, W. J.* International Journal of Acarology 2002, 28(1), 49.

“Identification of 2,4-dichlorophenol in Females of the American Dog Tick, Dermacentor variabilis (Acari- Ixodidae), and Its Possible Role as a Component of the Attractant Sex Pheromone”  Hanson, P.E.; Yoder, J.A.; Pizzuli, J.L.*; Sanders, C.I* Jounal of Medical Entomology 2002, 39(6), 945-947.

“Sex Pheromone Production and its relationship to water conservation: Studies on a Trichlorophenol in the American Dog Tick, Dermacentor Variabilis (Acari: Ixodidae)” Yoder, J.A.; Hanson, P.E; Pizzuli, J.L.*; Sanders, C.I.*; Domingus, J.L* International Journal of Acarology 2002, 28(4), 379-385.

“Internal and external mycoflora of the American dog tick, Dermacentor variabilis (Acari: Ixodidae), and its ecological implications” Yoder, J. A.; Hanson, P. E.; Zettler, L. W.; Benoit, J. B.*; Ghisays, F.*; Piskin, K. A.* Applied and Environmental Microbiology. Accpted for publication 2003.
 

    Presentations 2000-2003 (* denotes student presenter)
 
 

2003 Sanders, C. I., Domingus, J. L., Yoder, J. A. and Hanson, P. E. Identification of a new attractant, 2,4-dichlorophenol, in the American dog tick. Association of Southeastern Biologists, Washington, D.C.

2003 Sanders, C.I.*; Pizzuli, J.L.; Yoder, J.A.; Hanson, P. E.  Identification, In Vitro/ In Vivo Production and Implications of the Discovery of Two New Sex Pheromone in the American Dog Tick.  Annual meeting of the American Association for the Advancement of Science, Denver, CO.

2002 Domingus, J. L., Sanders, C. I., Hanson, P. E. and Yoder, J.A. Water conservation implication of 2,4,6-trichlorophenol sex pheromone in the American dog tick, Dermacentor variabilis.Wittenberg Student Research Symposium, Springfield, OH.

2002 Sanders, C. I., Domingus, J. L., Yoder, J.A. and Hanson, P. E. Detection of a new compound in the sex pheromone of the American dog tick.Wittenberg Student Research Symposium, Springfield, OH.

2002 Burke, W. J., Johnson, A. E., Hanson, P. E. and Yoder, J. A. Organic synthesis of a chlorophenol mixture that is highly attractive to ticks. The Association of Southeastern Biologists, Boone, NC.

2002 Pizzuli, J. L., Sanders, C. I., Yoder, J.A. and Hanson, P. E. Investigation on the timing of sex pheromone production and its detection in ticks. The Association of Southeastern Biologists, Boone, NC.

2002 Pizzuli, J. L., Sanders, C. I., Yoder, J.A. and Hanson, P. E. Timing and detection of sex pheromone production in ticks. Ohio Academy of Sciences, Columbus, OH.

2002 Burke, W. J., Johnson, A. E., Hanson, P. E. and Yoder, J. A. Synthetic preparation of a potent tick attractant for trap baits. Ohio Academy of Sciences, Columbus, OH.

2002 Sanders, Chris I.*, Burke, William J.*, Hanson, Peter E. and Yoder, Jay A: Importance of Chlorine Placement in the Role of 2,6-Dichlorophenol as a Sex Pheromone (Acari: Ixodidae).  Invited presentation, Entomological Society of America National Meeting December 15, 2001.

2001 Pizzuli, J. L.*, Sanders, C. I.*, Yoder, J.A. and Hanson, P. E. Isolation and Detection of the Sex Pheromone in American Dog Ticks. Wittenberg Student Research Symposium, Springfield, OH.

2001 Johnson, A. E.*, Burke, W. J.*, Hanson, P.E. and Yoder, J. A. Laboratory Synthesis of the Tick Sex Pheromone, 2,6-Dichlorophenol. Wittenberg Student Research Symposium, Springfield, OH.

2001 Pizzuli, J. L.*, Sanders, C. I.*, Yoder, J.A. and Hanson, P. E. The Investigation of Sex Pheromones in Ticks. Wittenberg Summer Seminar Series, Springfield, OH.

2001 Burke, W.  J.*, Johnson, A.  E.*, Hanson, P.E. and Yoder, J. A. Organic Synthesis of 2,6-Dichlorophenol. Isolation and Detection of the Sex pheromone in American Dog Ticks. Wittenberg Summer Seminar Series, Springfield, OH.

    Meeting Abstracts 2000-2002 (* denotes student author)

2001. Pizzuli, J. L*., Sanders, C. I.*, Yoder, J.A. and Hanson, P. E. Timing and Detection of Sex Pheromone Production in Ticks. The Ohio Journal of Science 102:13.

2001. Burke, W. J.*, Johnson, A. E.*, Hanson, P.E. and Yoder, J. A. Synthetic Preparation of a Potent Tick Attractant for Trap Baits. The Ohio Journal of Science, 102:13.

2001. Burke, W. J*.,  Johnson, A. E.*, Hanson, P.E. and Yoder, J.A. . Organic Synthesis of a Chlorophenol Mixture That is Highly Attractive to Ticks. Southeastern Biology. 49:121.

2001. Pizzuli, J. L.*, Sanders, C.I.*,  Yoder, J.A. and Hanson, P.E. Investigation on the Timing of Sex Pheromone Production and its Detection in Ticks. Southeastern Biology. 49:122.

2001. Pizzuli, J.  L.*, Sanders, C. I.*, Yoder, J.A. and Hanson, P. E. Isolation and Detection of the Sex Pheromone in American Dog Ticks. Wittenberg Student Research Symposium. p. 18.

2001 Johnson, A. E.*, Burke, W. J.*, Hanson, P.E. and Yoder, J. A. Laboratory Synthesis of the Tick Sex Pheromone, 2,6-Dichlorophenol. Wittenberg Student Research Symposium p. 12.
 

Email                Return To the Chemistry Department Home Page        Go to the Wittenberg University Home page